Use fibroblast growth factor 10 (FGF-10) to mediate epithelial-mesenchymal interactions, which are essential to lung development (Ware & Matthay. Am J Physiol Lung Cell Mol Physiol, 2002). FGF-10 is a member of the fibroblast growth factor family predominantly expressed by mesenchymal fibroblasts during embryonic development (Igarashi et al. J Biol Chem, 1998). FGF-10 has a role in mobilization and proliferation of lung-resident mesenchymal stem cells (MSCs) and protection and repair against acute lung injury (Tong et al. Sci Rep, 2016). It also has a role in regulating endodermal differentiation of human pluripotent stem cells to insulin-producing pancreatic-like cells (Takeuchi et al. Sci Rep, 2014). Human recombinant FGF-10 (KGF-2) from STEMCELL is animal component-free and comes lyophilized with ≥ 95% purity; EC50 ≤ 200 ng/mL; endotoxin levels verified ≤ 1 EU/μg protein. Alternative names: FGFA, Fibroblast growth factor-10, Keratinocyte growth factor-2.